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Table 1 lists adverse reactions that occurred in placebo-controlled clinical trials in patients who took at least 1 dose of study drugOnly treatment-emergent adverse reactions that occurred at a frequency of 2or more in any group treated with Imitrex tablets and that occurred at a frequency greater than the placebo group are included in Table 1.

Do not use Imitrex if you have used an MAO inhibitor in the past 14 daysA dangerous drug interaction could occurMAO inhibitors include isocarboxazidlinezolidmethylene blue injectionphenelzinerasagilineselegilinetranylcypromineand others.

Frequency not reportedAbortioncontusionsear infectionearnoseand throat hemorrhageexternal otitisfeeling of fullness in the ear(shearing disturbanceshearing lossMeniere’s diseaseotalgiaoverdosephotophobiasensitivity to noiseswelling of facetinnitus.

The risk of heart diseaseliver diseaseand high blood pressure increases with ageOlder adults may be more sensitive to the side effects of this drugespecially increased blood pressure and heart problems.

Another study of 125 patients concluded that panic-like symptoms may explain the chest pain and related side effects after sumatriptan administration in patients with high levels of anxietyRef]

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imitrex is not indicated for the prevention of migraine attacks.

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