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3Skinhair and nails Some indinavir users have reported thinner hair or temporary loss of hairDry skindry or cracked lipsand ingrown toenails have also been reported by indinavir usersThese symptoms are sometimes referred to as ectodermal dysplasiaFor more information about options to help manage this please see CATIE’s A Practical Guide to HIV Drug Side Effects

Body As A Wholeredistribution/accumulation of body fatsee PRECAUTIONSFat Redistribution

For many people with HIVthe use of ART has increased their CD4cell counts and decreased the amount buying pct. of HIV in their bloodviral loadThese beneficial effects help to reduce the risk of developing a life-threatening infectionNeither indinavir nor any other anti-HIV medication is a cure for HIVIt is therefore important that you do the following:

It may also be necessary to avoid drugs that do not affect indinavir drug levelsbut cause similar side effects.

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the results of one published study in hiv-infected men n 6 indicated that coadministration of indinavir 800 mg every 8 hours chronically with a single 25-mg dose of sildenafil resulted in an 11 increase in average auc0-8hr of indinavir and a 48 increase in average indinavir peak concentration cmax compared to 800 mg every 8 hours alone.

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