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Tell your doctor right away if you experience any of the symptoms listed in the hyzaar warnings section above, or any of the following serious side effects eye pain or vision problems little or no urination rapid weight gain feeling lightheaded, or like you might pass out extreme nausea loss of appetite increased thirst extreme drowsiness confusion mood changes pounding, fast, or slow heartbeat pale skin easy bleeding or bruising yellowing of the skin or eyes weak pulse signs of anaphylaxis, a severe allergic reaction may include hives, rash, itching, chest tightness, or swelling of the face, lips, tongue, or throat .

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Get emergency medical help if you have any of these signs of an allergic reactionhivesdifficulty breathingswelling of your facelipstongueor throat.

Before using this medicationtell your doctor or pharmacist your medical historyespecially ofgoutkidney diseaseliver diseaselupussevere loss of body water and mineralsdehydration

Hyzaar is a combination of losartanCozaarand hydrochlorothiazide and is used for treating high blood pressureLosartan is an oral medication that belongs to a class of drugs called angiotensin receptor blockersARBsOther ARBs include irbesartanAvaprovalsartanDiovanand candesartanAtacandAngiotensinformed in the blood by the action of angiotensin converting enzymeACEis a powerful chemical that attaches to angiotensin receptors found in many tissues but primarily on smooth muscle cells surrounding blood vesselsAngiotensin’s attachment to the receptors causes the muscles to contract and the blood vessels to narrowvasoconstrictwhich leads to an increase in blood pressurehypertensionLosartanmore specificallythe chemical formed when the liver converts the inactive losartan into an active chemicalblocks the angiotensin receptorBy blocking the action of angiotensinlosartan relaxes the musclesdilates blood vessels and thereby reduces blood pressure.

Avoid becoming overheated or dehydrated during exercisein hot weatheror by not drinking enough fluids.

Take Hyzaar exactly as prescribed by your doctorFollow all directions on your prescription labelYour doctor may occasionally change your doseDo not take this medicine in larger or smaller amounts or for longer than recommended.

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dofetilide or ketanserin because the risk of irregular heartbeat may be increased adrenocorticotropic hormone acth , barbiturates eg, phenobarbital , corticosteroids eg, prednisone , diuretics eg, furosemide , narcotic pain medicines eg, morphine , or other medicines for high blood pressure because they may increase the risk of hyzaar s side effects cholestyramine, colestipol, or nonsteroidal anti-inflammatory drugs nsaids eg, ibuprofen, celecoxib because they may decrease hyzaar s effectiveness diazoxide, digoxin, lithium, nondepolarizing muscle relaxants eg, tubocurarine , potassium, or potassium-sparing diuretics eg, spironolactone because risk of their side effects and toxic effects may be increased by hyzaar diabetes medicine eg, glipizide, metformin , insulin, or pressor amines eg, norepinephrine because their effectiveness may be decreased by hyzaar.

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