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The plasma clearance of methotrexate was slightly increased when these agents were co-administered in a pharmacokinetic study.

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If you need to be sedated for dental worktell your dentist you currently use this medicine.

When this medication is used with radiation treatmentit may rarely increase the risk of tissue and bone damageDiscuss the risks and benefits of your treatment with your doctor.

Before taking methotrexatetell your doctor or pharmacist if you are allergic to itor if you have any other allergiesThis product may contain inactive ingredientswhich can cause allergic reactions or other problemsTalk to your pharmacist for more details.

Methotrexate can be toxic to your organsand may lower your blood cell countsYour blood will need to be tested oftenand you may need an occasional liver biopsyYour cancer treatments may be delayed based on the results.

Generic Namemethotrexateoralmeth oh TREX ateBrand NamesRheumatrex Dose PackTrexallXatmep.

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peak serum concentrations of methotrexate occur 30 to 60 minutes after injection or by the oral route.

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